What a difference Moore's Law makes.
A few years ago, I briefly tried PersonalBrain, a visual notes organization tool. I thought the concept was interesting, but the program was too slow and it was too difficult to see enough information to be useful.
Skip forward two or three technology generations, double or triple my amount of monitor space, and those limitations have pretty much vanished. Yes, the software itself has evolved in that time, but the basic interface is unchanged. You still need a lot of space to see what's going on. It's just that now that space is available on my secondary monitor, leaving my main monitor free.
I don't yet know if PersonalBrain is going to become part of my toolkit, but the hardware has caught up enough to at least give it a reasonable trial.